Parkinson’s disease is a long-term condition that gradually worsens over time. In the early stages, medicines known as dopaminergic drugs can be highly effective. These treatments help replace the brain’s reduced supply of dopamine, often bringing significant relief. Many people feel better, regain independence, and are able to continue their usual daily activities.
As the disease advances, the nerve cells that produce dopamine become more damaged, and the medicines may not work as consistently. People may then experience periods when the effect of the medication wears off and symptoms return.
Doctors often describe two main phases:
- “on” phase – the period when medication is working well, symptoms are under control, and movement feels easier;
- “off” phase – the period when medication is wearing off and symptoms such as stiffness, slowness, or tremor reappear.
These phases can occur several times a day, which can be both frustrating and exhausting. Some people also develop a symptom known as “freezing” – a sudden, temporary inability to move, often while walking. This can be distressing and may increase the risk of falls.
It is important to remember that Parkinson’s disease is not the end of an active life. With the right treatment, rehabilitation, and support, many people continue to enjoy fulfilling and rewarding lives. At our care centres, we provide comprehensive support for people living with Parkinson’s disease – helping to manage symptoms, improve mobility, and maintain quality of life at every stage of the condition.
It is also important to remember that, unfortunately, as Parkinson’s disease progresses, its symptoms may change and become more pronounced over time.